Novel approach identifies people at risk of developing TB: Lancet study
A novel approach to studying the progression of tuberculosis (TB) from infection to disease can identify and treat people at increased risk of developing the disease that current methods of testing would not, according to a study published in The Lancet Microbe journal.
Researchers at the National Institute for Health and Care Research (NIHR) Leicester Biomedical Research Centre (BRC), UK, hope the findings could help with global efforts to reduce the spread of the disease.
TB is a bacterial disease that causes significant lung damage and can, without treatment, be fatal. It is spread in aerosol by inhaling droplets containing the bacteria.
Most people who become infected live with the infection and remain well. However, in a small proportion, the infection is not controlled and can progress to cause disease.
Current tests of TB infection use either a skin test or a blood test, called an interferon gamma release assay (IGRA) to detect an immune response to the infection. However, .

By Debra Moran

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